Abstract

Abstract

Background: Iron Deficiency Anaemia (IDA) constituting 66.2% of total anaemia cases, with 825 million women and 444 million men affected globally. Major symptoms are reduced appetite, dryness of skin, fatigue, weakness, dyspnoea on exertion, palpitation & pallor of the skin, mucous membranes & sclera etc. Several Iron contained medicines are conventionally used for the management of IDA whereas some of them have adverse reactions such as nausea, heartburn, constipation etc. Hence usage of safe and effective alternative correction of basic pathology of disease is to be taken. Objective: Primary objective is to find out the effectiveness of ayurvedic formulation termed as Harithakiyogam in Iron deficiency Anaemia. Materials and Methods: It is designed as quasi-interventional study. Total 23 participants of both male and female of age group 18-50 years having Haemoglobin level 8-12.9 g/dl for male and 8-11.9 g/dl for female were selected by consecutive sampling method. Participants were advised to take 500 mg of 1 tablet thrice daily after food for 3 months. Outcome parameters were Change in Haemoglobin level, red cell indices, Peripheral smear, RDW-CV and monitored on 0th day and 91st day. The obtained data were statistically analysed using Paired ‘t’ test. Results: After clinical trial, outcome parameters have statistically significant improvement (p<0.01) after the intervention period. Clinical symptoms were also significantly improved after the trial. Conclusion: The Trial drug was found effective in improving haemoglobin, red cell indices, microcytic hypochromic cells and RDW-CV value and clinically significant in reducing the associated symptoms.