Abstract

Abstract

Background: Hypothyroidism is a widespread metabolic disorder arising from reduced thyroid hormone activity, leading to diminished cellular metabolism and multisystem involvement. Its clinical manifestations can be comprehended in Ayurveda as a state of Agnimandya with Kapha–Vata predominance, resulting in dysfunction of Rasa and Meda Dhatu and obstruction of relevant Srotas. Ayurvedic management focuses on breaking of pathogenesis through Agnidipana, Amapachana, Dosha Shamana, and restoration of tissue metabolism, offering a root-oriented approach to long-term management. Objective-To elucidate the Ayurvedic pathogenesis (Samprapti) of hypothyroidism and outline relevant Ayurvedic principles of management. Material and Method: A narrative conceptual review was conducted using classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya, along with relevant contemporary scientific literature. Ayurvedic concepts related to metabolism and endocrine function were systematically analyzed and correlated with modern pathophysiological mechanisms. Conclusion: Hypothyroidism can be effectively interpreted within the Ayurvedic framework through Agnimandya and Dosha–Dhatu dysfunction. Understanding the pathogenesis allows formulation of rational Ayurvedic management strategies aimed at correcting the root cause and restoring metabolic balance.